This document presents a methodology which supports and enables the development of standards based business and information architectures that contribute to good quality of healthcare and patient safety. The methodology is used to develop deions of healthcare enterprises from different  aspects. Those aspects are covering what, how, where, who, when, why and are based on standards.st edition 2021-01 Health Informatics - Methodology for analysis of business and information needs of health enterprises to support standards based architectures Reference number ISO/TS 22272:2021(E) ？ ISO 2021 ISO/TS 22272:2021(E) COPYRIGHT PROTECTED DOCUMENT ？ ISO 2021 All rights reserved. Unless otherwise specified, or required in the context of i