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Synthesis of phenol-class azo derivatives of 4-aminosalicylic acid Synthesis of phenol-class azo derivatives of 4-aminosalicylic acid

Synthesis of phenol-class azo derivatives of 4-aminosalicylic acid

  • 期刊名字:中國化學(xué)快報(bào)(英文版)
  • 文件大?。?/li>
  • 論文作者:Shi Fei Sheng,Hui Xia Zheng,Ji
  • 作者單位:School of Pharmaceutical Science,First Clinical College
  • 更新時(shí)間:2022-11-28
  • 下載次數(shù):
論文簡介

To explore the better prodrug of 4-aminosalicylic acid (4-ASA) with higher activity and less side effects against the inflammatory bowel disease.4-ASA,after a succession of synthesis process,was conjugated with various carrier molecules to get seven azo derivatives of 4-ASA.All compounds were characterized by FT-IR,1H NMR,13C NMR spectras in detail.New derivatives of 4-ASA were definituded.

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